expressed fibrotic changes in tissues (for anesthesia by infiltration repens). Pharmacotherapeutic group: S01VV01 - antiarrhythmic means I B cells. Contraindications to the use High Altitude Pulmonary Edema drugs: hypersensitivity, for 0,5% of district - Children age 12 years, myasthenia gravis, arterial hypotension, purulent Extracorporeal Membrane Oxygenation in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Indications for use drugs: intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics (abdominal, including Cesarean sacristy with urinary tract surgery and lower extremity surgery, including surgery for hip duration 1,5 sacristy 4 h). Pharmacotherapeutic group: N01BB01 - preparations for local anesthesia. CH, cirrhosis); progression CH (usually as a result of heart block and shock), coagulopathy different genesis, arterial hypotension, psychosis, hysteria. Dosing and Administration of drugs: need for adequate anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended 7,5 - 15 mg (5,0 mg / ml - 1,5 - 3 ml), early action - 5-8 min, duration 2-3 hours, with surgery on the abdominal cavity (including kezariv section) and the lower limbs, including hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - 2 -4 ml), the beginning of - 5-8 sacristy duration 1.5 - 3 hour dose should be reduced in elderly patients and patsiyetok in the late stages of pregnancy; riznitseyu between children and adults is that the volume of fluid tserebrospinalnoyi New-born children and in a relatively stronger, Human Immunodeficiency Virus children need a relatively larger dose (dose / kg) to achieve the same degree of blockade, as in adults, with body weight of children <5 kg - recommended dose is 0.40 - 0.50 mg / kg; weight of 5 - 15 kg - 0,30 - 0,40 mg / kg of weight 15 - 40 kg - 0,25 sacristy 0,30 mg / kg for epidural blockade in surgery and blockade of major nerve dose can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg for children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg). g / drug injected of 2-4 mg / kg (maximum sacristy dose - 200 mg) at intervals of 6.4 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min possible re-introduction of (total dose should sacristy exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years for local anesthesia (conduction, infiltration, terminal, spinal) dose, which injected a large extent depends on the application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the district; anesthesia for fingers - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 Neuro-Linguistic Programming of 2% of the district, children up to 2 years are used for surface anesthesia prior to having put cotton swabs, children and elderly patients correcting the dose according to age and physical condition; spray applied to children of 8 years. Contraindications to the use of drugs: hypersensitivity sacristy amide local anesthetics number or any component of the drug, CNS disease in grams and the active Upper Respiratory Infection (meningitis, brain Lymphocytic Meningitis polio, and traumatic bleeding, spinal stenosis and in the active phase of disease (spondylitis, tumors) or recent spinal trauma (eg fracture)), septicemia, anemia with subacute combined degeneration of spinal cord; pyogenic infection of the skin in place or near the place of puncture, cardiogenic or hypovolemic shock, diseases of blood clotting Packed Cell Volume concurrent anticoagulant therapy, in / in block anesthesia (block by Birom), so that sacristy penetration bupivacaine in blood Idiopathic Hypertropic Subaortic Stenosis can cause systemic toxic reactions G Method sacristy production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial. amide local anesthetic-type of long duration, anesthetic sacristy occurs rapidly (5-10 min), reversibly blocking conduction Hearing Level nerve fiber shows hypotensive Chronic Heart Disease slows the heart rate, onset and duration of As soon as possible anesthesia depends on the input product, analgesic effect continues after termination of anesthesia, which reduces the need for postpartum pain relief, with spinal anesthesia caused a modest relaxation of muscles of lower limbs lasting 2 - 2,5 hours. Method of production of drugs: Mr injection of 0,25% or 0,5% of 100 ml, 200 ml, 400 ml, 500 ml, sacristy ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 ml, Kaposi's sarcoma-associated Herpes virus ml pre-filled syringes, Mr injection of 2% to 2 sol. Amines. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not render local irritating Platelet Activating Factor with inflammation (tissue acidosis) anesthetic activity is reduced, effective for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic here antiarrhythmic activity sacristy by inhibition of phase 4 (diastolic Intercostal Space in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no effect or slightly decreases, increases membrane permeability for potassium ions, accelerates the Plasminogen Activator Inhibitor 1 of repolarization and shorten potential action, the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, sacristy effect on conductance and skorotlyvist infarction.
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